2. Signaling Pathways
  3. GPCR/G Protein
  4. LPL Receptor
  5. S1PR2 Isoform
  6. S1PR2 Inhibitor

S1PR2 Inhibitor

S1PR2 Inhibitors (2):

Cat. No. Product Name Effect Purity
  • HY-176533
    S1PR5-IN-1
    		Inhibitor 99.58%
    S1PR5-IN-1 (Compound 7a) is a highly selective S1PR5 antagonist and orally bioavailable inhibitor with a human S1PR5 IC50 of 85.4 nM and human S1PR5 Ka of 2.173 nM.S1PR5-IN-1 binds to S1PR5 and inhibits natural killer cell migration toward sphingosine-1-phosphate.S1PR5-IN-1 can be used for the research of multiple sclerosis.
  • HY-120409
    AB1
    		Inhibitor
    AB1 is a highly selective S1P2 receptor antagonist (IC50=3.5 nM). AB1 inhibits sphingosine-1-phosphate (S1P) signaling, suppressing tumor cell migration, angiogenesis, and profibrotic mediator CTGF expression while inducing apoptosis. AB1 is promising for research of solid tumors.